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Moreover, although randomized designs mitigate healthy-user bias, participants enrolled in long-term cardiovascular outcome trials may represent a healthier, more adherent subset of patients, potentially limiting generalizability

Inka Miambres Donaire, miembro del rea de Obesidad de la Sociedad Espaola de Endocrinologa y Nutricin (SEEN): los estudios acerca del riesgo de sarcopenia no son concluyentes, puesto que, si bien se pierde masa muscular, lo ms importante -que es la funcionalidad- no parece alterarse en los ensayos clnicos